SOLUTION:
A straight substitution of x=4 leads to the indeterminate form 00 which is meaningless.
Therefore, to evaluate the limit of the given function, we proceed as follows
x→4lim(x2−16x3−64)=x→4lim((x+4)(x−4)(x−4)(x2+4x+16))=x→4lim(x+4x2+4x+16)=4+4(4)2+4(4)+16=848=6 (Answer)